Aspergillus nidulans
Teleomorph: Emericella nidulans
On Czapek dox agar, colonies are typically plain green in color with dark red-brown cleistothecia developing within and upon the conidial layer. Reverse may be olive to drab-gray or purple-brown. Conidial heads are short, columnar (up to 70 x 30 um in diameter) and biseriate. Conidiophores are usually short, brownish and smooth-walled. Conidia are globose (3.0-3.5 um in diameter) and rough-walled. RG-2 organism.
Culture of Aspergillus nidulans.
Conidial head of A. nidulans.
Note: conidial heads are short, columnar and biseriate.
Conidiophores are usually short, brownish and smooth-walled.
Conidia are globose and rough-walled.
Cleistothecium of Emericella nidulans (anamorph A. nidulans)
showing numerous reddish-brown ascospores.
Cleistothecia of A. nidulans are often surrounded by a mass of
Hülle cells which are up to 25 um in diameter.
Thick-walled Hülle cells of Emericella nidulans.
MIC data is limited. Antifungal susceptibility testing of individual strains is recommended.
| Antifungal | MIC ug/mL | Antifungal | MIC ug/mL |
||
Range |
MIC90 |
Range |
MIC90 |
||
| Itraconazole | 0.03-8 |
0.25 |
Amphotericin B | 0.125-4 |
2 |
| Voriconazole | 0.125-4 |
0.25 |
Caspofungin | 0.125-8 |
nd |
| Posaconazole | 0.03-1 |
0.25 |
|||
Clinical significance:
Aspergillus nidulans is a typical soil fungus with a world-wide distribution. It has also been reported as a causative agent of aspergillosis in humans and animals.
Mycosis: Aspergillosis
Further reading:
De Hoog G.S. and J Guarro. 1995. Atlas of clinical fungi. Centraalbureau voor Schimmelcultures, Baarn and Delft, The Netherlands.
Kwon-Chung, K.J. and J.E. Bennett. 1992. Medical Mycology. Lea & Febiger, Philadelphia and London.
