Sepedonium sp.

Colonies are moderately fast growing, usually white to golden yellow, suede-like to downy, becoming fluffy with age. Conidiophores are hyaline and nonspecialized, resembling short branches of the vegetative hyphae. Conidia are terminal, solitary, or in clusters, one-celled, globose to ovoid, 7 to 17 um, hyaline to amber, smooth to verrucose and usually with a thick wall.  RG-1 organism.

Conidia of Sepedonium sp.

Clinical significance:

Sepedonium species are common soil fungi and parasites of fleshy fungi however they closely resemble Histoplasma capsulatum. Therefore, positive identification of the latter, requires conversion of the mould form to the yeast phase by growth at 37C on enriched media or by exoantigen test.

Mycosis: Hyalohyphomycosis

Further reading:

McGinnis, M.R. 1980. Laboratory handbook of medical mycology. Academic Press, London, UK.