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Phaeoacremonium parasiticum

Synonymy: 
Phialophora parasiticum

The genus Phaeoacremonium initially accommodated isolates with features similar to those seen in both Acremonium and Phialophora. It differs from the former by having pigmented hyphae and conidiophores and from the latter by having indistinct collarettes and warty conidiogenous cells (Revankar and Sutton, 2010).

Phaeoacremonium currently consists of 46 species with P. parasiticum and P. krajdenii recognised as the predominant species associated with human infections (Mostert et al. 2005). Other species have also been isolated from clinical cases i.e. P. alvesii, P. amstelodamense, P. griseorubrum, P. minimum, P. rubrigenum, P. tardicrescens, and P. venezuelense. Infections caused by P. parasiticum include subcutaneous abscesses, thorn-induced arthritis, and disseminated infection (Revankar and Sutton, 2010, Gramaje et al. 2015).

RG-2 organism.

Morphological Description: 
Cultures usually slow growing, suede-like with radial furrows, initially whitish-grey becoming olivaceous-grey with age. Hyphae hyaline, later becoming brown and some becoming rough-walled. Phialides are brown, thick-walled, slender, acular to cylindrical slightly tapering towards the tip, 15-50 μm long, often proliferating, with small, funnel-shaped collarettes. Conidia, often in balls, are hyaline, thin-walled, cylindrical to sausage-shaped, 3-6 x 1-2 μm, later inflating. Maximum growth temperature 40C.

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