Skip to content

Meyerozyma guilliermondii

Synonymy: 
Candida guilliermondii

Meyerozyma guilliermondii has been isolated from numerous human infections, mostly of cutaneous origin. It is also found on normal skin and in sea water, faeces of animals, fig wasps, buttermilk, leather, fish and beer.

RG-1 organism.

Culture: 
White to cream-coloured smooth, glabrous, yeast-like colonies.

Microscopy: 
Spherical to subspherical budding yeast-like cells or blastoconidia, 2.0-4.0 x 3.0-6.5 µm.

India Ink Preparation: 
Negative - no capsules present.

Dalmau Plate Culture: 
Branched pseudohyphae with dense verticils of blastoconidia.

Molecular Identification:
ITS sequencing recommended.

MALDI-TOF MS: 
Able to accurately identify this species.

Physiological Tests: + Positive, - Negative, v Variable, w Weak, s Slow, nd No Data
Germ Tube - L-Sorbose v L-Arabinose v D-Glucitol v
Fermentation Sucrose + D-Arabinose v 𝝰-M-D-glucoside v
Glucose + Maltose + D-Ribose + D-Gluconate v
Galactose v Cellobiose v L-Rhamnose v DL-Lactate v
Sucrose + Trehalose + D-Glucosamine + myo-Inositol -
Maltose - Lactose - NAD-glucosamine + 2KD-Gluconate +
Lactose - Melibiose v Glycerol + D-Glucuronate nd
Trehalose + Raffinose + Erythritol - Nitrate -
Assimilation Melezitose v Ribitol + Urease -
Glucose + Soluble Starch - Galactitol v 0.1% Cyclohgeximide v
Galactose + D-Xylose + D-Mannitol v Growth at 37C v

Key Features: 
Germ tube negative yeast and sugar assimilation pattern.

Antifungal Susceptibility: Meyerozyma guilliermondii (Diekema et al. 2009 and Australian National data); MIC µg/mL.
No <0.03 0.06 0.125 0.25 0.5 1 2 4 8 16 32 >64
AmB 198 4 9 70 70 27 9 2 1 1 5
FLU 199 1 4 5 75 75 7 11 4 7
VORI 197 36 88 52 9 3 1 2 6
POSA 194 10 14 47 79 30 4 4 6
ITRA 24 6 3 12 2 1
ANID 120 1 2 6 5 9 41 48 8
MICA 13 4 4 10 14 39 29 8 1
CAS 175 2 9 24 35 63 25 8 2 3 4
5FC 24 8 12 1 1 1 1

Back to Yeast-like Fungi

School of Biological Sciences
Address

THE UNIVERSITY OF ADELAIDE
SA 5005 AUSTRALIA

Contact

Dr David Ellis
Email