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Mould Identification: A Virtual Self Assessment

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Unknown 28 = Coniochaeta hoffmannii

Case History
A 44-year-old HIV+ man on antiretroviral therapy presented with chronic sinusitis. A CT scan revealed extensive erosive pansinusitis. An antral washing was performed and hyphal elements were observed on direct microscopy and the culture shown below was grown.
Direct Microscopy (PAS)

Periodic Acid-Schiff (PAS) stained smear showing septate hyphal elements.
Culture

Colonies are flat, smooth, moist, pink to orange, with regular and sharp margin; reverse pink.
Microscopy

Hyphae are narrow, hyaline, producing conidia laterally from small collarettes directly on the hyphae, or from lateral cells which are sometimes arranged in dense groups; lateral cells flask-shaped or nearly cylindrical. Conidia are hyaline, smooth- and thin-walled, broadly ellipsoidal to cylindrical or allantoid, produced in slimy heads
Comment: The genus Coniochaeta is morphologically similar to Phialemonium. Coniochaeta hoffmannii has been associated with cases of subcutaneous infections, keratitis, sinusitis, peritonitis, and canine osteomyelitis. Coniochaeta mutabilis has been described to be a causative agent of human peritonitis, endocarditis, endophthalmitis, and keratitis.

About Coniochaeta Back to Virtual Assessment

What is your identification?

Pleurostomophora richardsiae
Myrmecridium schulzeri
Coniochaeta hoffmannii

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School of Biological Sciences
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Dr David Ellis
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