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Mould Identification: A Virtual Self Assessment

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Unknown 25 = Acrophialophora fusispora

Case History
A 14 year old boy with cystic fibrosis presented with chronic airway colonization. Repeated sputum samples grew the fungus shown below.
Culture

Colonies (SDA) fast growing, greyish-brown with a black reverse.
Microscopy

Conidiophores arising singly, terminally and laterally from the hyphae, erect, straigt or slightly flexuose, tapering towards the apex, pale brown, rough walled, with whorls of phialides on the upper part.

Microscopy

Phialides flask shaped with a long and narrow neck, hyaline, smooth walled or echinulate.

Microscopy

Conidia in long chains, limoniform, one-celled, pale brown, finely echinulate with distinct spiral bands.
Key Features:  Hyphomycete with flask shaped phialides producing long chains of one-celled, limoniform, pale brown conidia, with distinct spiral bands.  Temperature: optimum 40C; maximum 50C.

Comment: The genus Acrophialophora contains 3 species and is most commonly associated with soil, especially from India. A. fusispora is a rare human pathogen. BSL-1 organism.

About Acrophialophora Back to Virtual Assessment

What is your identification?

Phaeoacremonium parasiticum
Acrophialophora fusispora
Ochroconis humicola

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Dr David Ellis
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