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Mould Identification: A Virtual Self Assessment

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Unknown 40 = Apophysomyces elegans

Case History
A 45 year old man with full-thickness burns to his legs and feet presented with blistering on the medial aspect of his right foot. A biopsy revelled the presence of broad in-frequently septate hyphae and culture shown below was isolated.
Clinical Presentation

The blistering on the medial aspect of the right foot was the first sign of infection.
Direct Microscopy

Tissue morphology in zygomycosis showing distinctive infrequently septate thin walled hyphae with focal bulbous dilations and irregular branching, typical for those species belonging to the Mucorales.
Culture

Colonies are fast growing, white becoming creamy white to buff with age, downy with no reverse pigment, and are composed of broad, sparsely septate (coenocytic) hyphae typical of a zygomycetous fungus.
Microscopy

Apophysomyces elegans showing distinctive funnel-shaped apophyses and a conspicuous pigmented sub-apical thickening below the apophysis.
Comment: Apophysomyces elegans is a rare human pathogen usually associated with invasive lesions following traumatic implantation of the fungus through the skin. It is a soil fungus with a tropical to sub-tropical distribution.

About Apophysomyces Back to Virtual Assessment

What is your identification?

Lichtheimia corymbifera
Apophysomyces elegans
Rhizomucor miehei

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Dr David Ellis
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