Mould Identification: A Virtual Self Assessment
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Unknown 41 = Aspergillus fumigatus
|A 35-year-old retired painter with chronic myeloid leukaemia with acute GVH developed a necrotising pneumonia with a bronchopleural fistula. Lobectomy showed the presence of filamentous hyphae and the culture below was isolated.|
Aspergillosis of the lung. Methenamine silver stained tissue section showing conidial heads of A. fumigatus in an alveolus air sac (top) and dichotomously branched, septate hyphae (bottom) in tissue.
On Czapek dox agar, colonies show typical blue-green surface pigmentation with a suede-like surface consisting of a dense felt of conidiophores.
Conidial heads are typically columnar (up to 400 x 50 um but often much shorter and smaller) and uniseriate. Conidiophores are short, smooth-walled and have conical-shaped terminal vesicles which support a single row of phialides on the upper two thirds of the vesicle. Conidia are produced in basipetal succession forming long chains and are globose to subglobose (2.5-3.0 um in diameter), green and rough-walled. Note: this species is thermotolerant and grows at temperatures up to 55C. RG-2 organism.
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