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Mould Identification: A Virtual Self Assessment

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Unknown 71 = Sepedonium chrysospermum

Case History
A 35 year-old HIV+ patient presented feeling unwell, with a cough, diarrhea and weight loss. A BAL grew the fungus seen below.
Culture

Colonies are moderately fast growing, usually white to golden yellow, suede-like to downy, becoming fluffy with age.
Microscopy

Conidiophores are hyaline and nonspecialized, resembling short branches of the vegetative hyphae. Conidia are terminal, solitary, or in clusters, one-celled, globose to ovoid, 7 to 17 um, hyaline to amber, smooth to verrucose and usually with a thick wall.  RG-1 organism.
Comment:
Sepedonium species are common soil fungi and parasites of fleshy fungi however they closely resemble Histoplasma capsulatum. Therefore, positive identification of the latter, requires conversion of the mould form to the yeast phase by growth at 37C on enriched media or by exoantigen test.

About Sepedonium Back to Virtual Assessment

What is your identification?

Chrysosporium pannicola
Histoplasma capsulatum
Sepedonium chrysospermum

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Dr David Ellis
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