Mould Identification: A Virtual Self Assessment
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Unknown 1 = Paecilomyces variotii
|A 4 year old boy with chronic granulomatous disease presented with extensive alveolar opacity and prominant interstitial marking on CRX. On biopsy granulomas containing fungal elements were seen on histopathology. The fungus shown below was isolated.|
Methenamine silver stained tissue section showing branched, septate hyphae.
Colonies are fast growing, powdery to suede-like and yellow-brown or sand coloured.
Conidiophores bearing vericillately arranged branches bearing phialides. Phialides are swollen at their bases, gradually tapering into a rather long and slender neck. Conidia are single-celled or in short chains, ellipsoidal to fusiform, hyaline to yellow, 3-5 x 2-4 um and are produced in basipetal succession from the phialides.
Chlamydoconidia are usually present, singly or in short chains, brown, subspherical to pyriform, 4-8 um diam, thich-walled to slightly verrucose.
Comments: Paecilomyces variotii is a common environmental mould that is widespread in composts, soils and food products. It is known from substrates including food, indoor air, wood, soil and carpet dust. It is a causative agent of mycotic keratitis and of hyalohyphomycosis in the immunocompromised patient.
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