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Mould Identification: A Virtual Self Assessment

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Unknown 16 = Exophiala jeanselmei

Case History
A 26-year-old male renal transplant patient prsented with a nodular lesion on the right leg. A tissue biopsy was taken and histological examination revealed the presence of fungal hyphae and cultures grew the fungus shown below.
Direct Microscopy (PAS stained tissue section)

Brown pigmented (not seen in this PAS preparation), branching septate hyphae are typical of phaeohyphomycosis.

Colonies are initially smooth, greenish-grey to black, mucoid and yeast-like, becoming raised and developing tufts of aerial mycelium with age, often becoming dome-shaped and suede-like in texture. Reverse is olivaceous-black.

Yeast-like cells, torulose hyphae, conidiophores, annellides and conidia of E. jeanselmei.

Microscopic view

Annellide and conidia of E. jeanselmei.
Comment: Exophiala species are common environmental fungi often associated with decaying wood and soil enriched with organic wastes. However, several species notably E. jeanselmei, E. moniliae and E. spinifera, are well documented human pathogens. Clinical manifestations include mycetoma (especially for E. jeanselmei), localized cutaneous infections, subcutaneous cysts, endocarditis and cerebral and disseminated infections. Phaeohyphomycosis caused by Exophiala species has been reported in both normal and immunosuppressed patients.

About Exophiala jeanselmei Back to Virtual Assessment

What is your identification?

Phaeoacremonium parasiticum
Hortaea werneckii
Exophiala jeanselmei

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School of Biological Sciences



Dr David Ellis